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The COVID19 pandemic has affected the entire world, touching all aspects of our lives. The uncertainty and the rapid spread has the medical community working diligently on containing the pathogen. This has been quite a daunting task. Nevertheless, progress has been made with one major caveat: promising results can fall short in the long run. Development of a vaccine is perhaps the best hope to end this pandemic. Vaccine development normally take syears to complete, but the corona virus is part of the family of viruses that cause the common cold and also caused the severe acute respiratory syndrome (SARS) as well as the Middle East Respiratory Syndrome (MERS). Past research on these viruses gave scientists a head start in identifying potential approaches. The Corona virus has earned its own trademark label, because of its appearance, particularly the now familiar spikes. Called S proteins, these spikes attach themselves to the surface of human cells. The vaccine, once created and perfected, would act by preventing the S protein from attaching itself to cells, thus preventing the virus from reproducing. A vaccine development timeline follows standard protocol. The gravity of this pandemic has placed research and development on a fast-track approach. The protocol begins with vaccinating animals. Phase I testing in humans follows. The focus of Phase II is formulating and establishing dosage criteria to determine the efficacy. Phase III involves testing the vaccine on a vast number of volunteers. The caveat here is that human trials generally take twelve to eighteen months to complete. In some cases, the trials reveal that a potential vaccine may prove to be ineffective and possibly harmful. The good news is that vaccines do not just work on solitary, specific individuals. They can protect entire populations. The reasoning behind this is that when enough individuals receive the vaccine, the opportunity for an outbreak is minimized so even those people who are not immunized benefit. What essentially occurs is the virus does not have enough hosts to establish a foothold and eventually disappears. If you view this entire situation from a positive perspective, the pandemic has given all of us time and opportunities to take a look at our lives and see what truly is important-family, friends and social interactions. For all of us, no matter what age group, celebrations with friends will take on an even greater meaning. Let us hope that this new awakening and true appreciation of life will remain with us forever. by Ihor Magun , MD, FACP COVID Some Thoughts on A Note of Appreciation From Dr. Magun Working with Tamara Cornelison for so many years has been a pleasure and rewarding experience. I know she will always excel in whatever she chooses to pursue. Thank you for giving me the opportunity to work with you. Our Life | Наше життя 35
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